As part of a collaborative research project, the candidate will be responsible for implementing biochemical techniques for the expression and purification of tagged mycobacterial proteins for a proteomic analysis of their interactomes by mass spectrometry. These approaches will make it possible to study the molecular players involved in lipid transport in mycobacteria.
In-depth knowledge of protein biochemistry Theoretical knowledge of proteomics required Knowledge of proteomic data analysis tools
The recruited person must demonstrate
The person recruited should have a Master's degree. An experience in mass spectrometry field of at least 3 years would be a plus.
The work will be carried out at the Institute of Pharmacology and Structural Biology (IPBS) (UMR 5089) in the “Proteomics and Mass Spectrometry of Biomolecules” team directed by Dr. Odile Schiltz in collaboration with the “Molecular Mycobacterial Pathogenesis ” team directed by Dr. Christophe Guilhot. The mission will be carried out under the supervision of a researcher from the proteomics team and will require working closely with the biological researchers of the collaborating team. For several years, the team has been developing innovative strategies in proteomics, in order to better understand the interaction dynamics of proteins and their mechanisms of action in order to study protein function. The team is made up of twenty people with complementary expertise in mass spectrometry, biochemistry and bioinformatics, and is equipped with state-of-the-art instrumentation as well as a solid informatic infrastructure.
IPBS is a unit comprising around 250 people spread over 17 research teams and drawing on several technological platforms, located in Toulouse in the south-west of France.
The candidate is asked to send a CV and a cover letter including (if possible) the contact details of one or two referents.
*To apply * Go to Portail Emploi CNRS