Post-doctoral fellowship in biological chemistry, proteomics and interactomics at ANSES Fougères

Posted 16 Jun 2022

French Agency for Food, environmental and occupational Health & Safety (ANSES)

France (Post Doc)

https://www.anses.fr/en


The post doctoral position is available (subject to acceptance) in the Toxicology of contaminants Unit of the French Agency for Food, environmental and occupational Health & Safety (ANSES) at Fougères (Brittany region, France). Research of interest of the unit are toxicology and cell biology but more recently proteomics, metabolomics and exposomics in order to decipher biological response associated to xenobiotics exposure.

The aim of the project is to develop interactomics to study the interaction of food contaminants with proteins. The team has opportunity to answer a call launched by the Brittany region for a two-years post-doctoral fellowship at ANSES Fougères (France). As far as we know, the grant has more chance to be funded if a candidate is proposed. We search a PhD student or a post-doc may be interested to candidate. Nevertheless, the rules are strict concerning the candidate. He/she can be of any country including France as soon as he/she has spent more than 18 months outside France between the 1st of May 2019 and the beginning of the grant. The salary is attractive (76 kE maximum for 2 years). The deadline is at the beginning of July 2022 (for a response in october and a start from early-2023 but before end of 2023). A brief summary of the project is added below.

The project is to characterize metabolic and toxicological mechanisms induced by xenobiotics (pesticides and toxins) by studying theirs interactions with proteins in biological fluids and liver cells. Several methodologies based on chemistry, biochemistry and proteomics will be developped to identify and/or purify protein complexes associated to xenobiotics.

The team “Toxicology of contaminants” is held by Dr. Valérie Fessard and includes around 10 persons (scientists, technicians and students) with strong and original interdisciplinary skills including chemistry, toxicology, cellular and molecular biology. We are mostly dealing with hazard characterization of food contaminants. The laboratory is well equipped including image analysis for High Content Analysis and 2 HR-MS mass spectrometers for proteomics and metabolomics (Q-Exactive Plus and Vion IMS Q-TOF) as well as cell culture and animal facilities. We expect to get early next year a nano-LC system HR-MS.

Skills/Qualifications: • PhD in analytical chemistry and/or proteomics • Required experience in proteomics analyzes by LC-MS/MS • Required knowledge in chemistry and analytical chemistry • Desired skills in Python, R, and biostatistics • Desired knowledge in cell biology

Perks

(i) The salary is attractive (76 kE maximum for 2 years). (ii) The laboratory is well equipped including image analysis for High Content Analysis and 2 HR-MS mass spectrometers for proteomics and metabolomics as well as cell culture and animal facilities. We expect to get early next year a nano-LC system HR-MS.

How to Apply

Important:
(i) The applicant can be of any country including France as soon as he/she has spent more than 18 months outside France between the 1st of May 2019 and the beginning of the grant.
(ii) The deadline is at the beginning of July 2022 (for a response in october and a start from early-2023 but before end of 2023)

Contact: thibaut.leger@anses.fr